Course description
Molecular Biology – Part 3: RNA Processing and Translation
In Part 3 of 7.28x, you’ll explore translation of mRNA to protein, a key part of the central dogma of biology. Do you know how RNA turnover or RNA splicing affects the outcome of translation? Although not official steps in the central dogma, the mechanisms of RNA processing strongly influence gene expression.
Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?
Take a behind-the-scenes look at modern molecular biology, from the classic experimental events that identified the proteins and elements involved in translation and RNA splicing to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We've designed the assessments in this course to build your experimental design and data analysis skills.
Let’s explore the limits of our current knowledge about the translation machinery and mechanisms of RNA turnover and splicing. If you are up for the challenge, join us in 7.28.3x Molecular Biology: RNA Processing and Translation.
Upcoming start dates
Suitability - Who should attend?
Prerequisites
7.00x Introduction to Biology or similar (undergraduate biochemistry, molecular biology, and genetics), 7.28.1x and 7.28.2x Molecular Biology or similar (advanced understanding of the central dogma)
Outcome / Qualification etc.
What you'll learn
- How to compare and contrast translation in bacteria and eukaryotes
- How to describe several mechanisms of RNA turnover and RNA splicing
- How to analyze protein structures to infer functional information
- How to design the best experiment to test a hypothesis
- How to interpret data from translation and RNA processing experiments
Training Course Content
- Translation I – Overview and Key Players
- Translation II – Elongation
- Translation III – Initiation and Termination
- Translation IV – Regulation of Translation
- RNA Splicing I – Mechanisms
- RNA Splicing II – Proofreading and Alternative Splicing
- RNA Turnover I – Assays and General Mechanisms
- RNA Turnover II – Specific Bacterial and Eukaryotic Mechanisms
Course delivery details
This course is offered through Massachusetts Institute of Technology, a partner institute of EdX.
4-8 hours per week
Expenses
- Verified Track -$99
- Audit Track - Free